據悉，欧盟2021年4月9日，评估歐盟食品安全局就一種食品酶製劑異麥芽糖合酶（isomaltulose synthase）的种异安全性評價發布意見。

據了解，麦芽酶這種食品酶製劑是糖合由Serratia plymuthica strain Z12A生產的。經過評估，安全專家小組得出結論，欧盟該食品酶製劑在預期的评估使用條件下不會引起安全問題。部分原文報道如下：

The 种异food enzyme isomaltulose synthase (sucrose glucosylmutase; EC 5.4.99.11) is produced with Serratia plymuthica strain Z12A by BENEO‐Palatinit GmbH. The food enzyme is used only in the form of an immobilised preparation of non‐viable cells for the production of isomaltulose. Residual amounts of total organic solids (TOS) are removed by the purification steps applied during the production of isomaltulose consequently, dietary exposure was not calculated. Genotoxicity tests did not indicate safety concern. The systemic toxicity was assessed by means of a repeated dose 90‐day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1,011 mg TOS/kg body weight (bw) per day, the highest dose tested. Similarity of the amino acid sequence of the enzyme to those of known allergens was searched and no match was found. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood of such reactions to occur is considered to be low. based on the data provided, the use of an immobilised food enzyme and the removal of TOS during the production of isomaltulose the Panel concluded that this food enzyme preparation does not give rise to safety concerns under the intended conditions of use.

資料來源：食品夥伴網。如涉及作品內容、麦芽酶版權等問題，糖合請與本網聯係刪除。安全

相關鏈接：異麥芽糖，欧盟食品安全